News:

3rd Science to Market conference in Vienna 2010:

click here for full article

EAPB organizes 2nd Science to market conference:

The EAPB was founded in Berlin in 2000, among the foundation members were pharmacists from the Institute of Pharmacy, Freie Universität (FU) Berlin. Prof. Müller from the Berlin pharmacy institute was the first president, the location of EAPB was at the Freie Universität Berlin (now moving away from Berlin). Meanwhile EAPB established as the leading biotechnology organization in Europe, and has established its own conference “Science to Market”. Below you find the press release for the 2^nd S2M in Hannover 2009.

click here for full article

Cosmetic Innovation Award - April 2009:

For the 7th time the "European Innovation Award for Cosmetics and Chemical Excipients" was awarded in the categories innovative "naturals", "functionals/recipients" and "most innovative marketed product" of the year. The award was initiated by BSB Dr. Riedel Hamburg, and is supported by the cosmetic industry. Two juries decide about the winners. This year the award ceremony took place in Munich on 22 April 2008. In the category "functionals/recipients" the first award was given for "Symhelios 1031" to Symrise, the 2nd for the development of "Nanodiamonds" to PharmaSol, represented by Dr. C. Keck Head R&D, the 3rd award for "Luviquat Sensation" to BASF. Scientific cooperation partner of PharmaSol was Prof. R.H. Müller. Most innovative üproduct of the year was the "Mastercreme" by Juvena, 1st award in the category "naturals" was given to Arch for the product "Metabiotics Resveratrol". More detailed Info: http://www.bsb-cosmetic.de/de/2009.htm

Picture of the innovation award winners 2009

Last row: very right: Dr. Riedel - initiator of the awards

Middle row: Dr. Keck/PharmaSol GmbH Berlin and Prof. Müller/Freie Universität Berlin (2nd and 3rd from left), Dr. Gruber/Arch (very right)

Front row: Ms. Frei and Ms. Ibanez/Juvena (2nd and 3rd from left), Dr. Johncock/Symrise (4th from left) and Ms Boulding/Arch (very right).

23^th March 2009 - "Leaving Ball" of the Institute of Pharmacy terminated

In July 2008 (summer term semester) and February 2010 (winter term semester) there was no leaving ball because of too low interest of the students in their final term to participate, despite the availability of funding to co-sponsor the ball. Due to this lack of interest, therefore for the time being no leaving balls will be organized. Prof. Müller dropped his role as university patron of the ball.

17^th December 2008: Innovationspreis-Newsletter 2008

5^th December 2008:    Preise für Innovation vergeben!

“Innovation Awards of the Counties of Berlin-Brandenburg 2008“

Each year Berlin and Brandenburg recognize innovation in their counties by the “Innovation Award”, given to companies or individuals. In general, there are about 150 applications each year, and about 4 awards are granted. In 2008, the “nanodiamonds” were selected for the Innovation Award, a joint development by PharmaSol GmbH/Dr. C. Keck together with Prof. R. Müller/Free University of Berlin and the company P.W. Beyvers in Berlin. Other awardees in 2008 were e.g. Siemens AG for the development of a new gas turbine and the Charité hospital in Berlin (Prof. Speck) for a new therapeutic approach.

Innovationspreis 2008 Berlin/Brandenburg

Preisübergabe: Mitte Dr. Keck und Prof. R.H. Müller, dann Senator Wolf/Berlin

und Wirtschaftsminister Junghanns/Brandenburg (von rechts nach links)

Preisträger von rechts: Dr. R. Weigl als Vertreter der Firma P.W. Beyvers,

Frau Dr. C. Keck/PharmaSol GmbH und Prof. R.H. Müller

Dr. Cornelia Keck und Prof. Rainer H. Müller

mit Innovationspreis

Berliner Morgenpost: 06.12.2008     07.12.2008     Scan

Der Tagesspiegel: 06.12.2008     Scan

Märkische Allgemeine: Scan

Rhein Zeitung: Scan

Video: Nanodiamanten für die Haut – Smart Crystals®

November 2008:

NLC in the press, cosmetic journal "Profi Kosmetik", interview Dr. Rimpler, CSO of Dr. Rimpler GmbH/Germany, the company which placed the first cosmetic products with NLC on the market in 2005. (Article in German)

click here for full article

13th November 2008:   Prof. Müller nominated for the Innovation Award Berlin-Brandenburg 2008 (Innovationspreis Berlin-Brandenburg 2008)

It is the 25th anniversary of the Innovation Award Berlin-Brandenburg. In a press conference the 7 nominees for the Award 2008 were announced in the Liebermann Building in Berlin on 13 November 2008. The final 4

winners will be presented to the public during the official award ceremony on Friday 5 December 2008. Since its introduction about 110 awards have been given, promoting the future developments of these

innovations and the companies. The research consortium Dr. C. Keck/PharmaSol GmbH, D. Karlowswki/P.M. Beyvers GmbH and Prof. Müller were nominated with the innovation "Nanodiamonds" (Nanodiamanten) for

improved delivery of cosmetic actives and pharmaceutical drugs. Another area of application are nutritional supplements. It is the second time that Prof. Müller was nominated, in 2006 he was nominated for the lipid

nanoparticle NLC technology together with the Berlin company Chemisches Laboratorium Dr. Richter (CLR) GmbH.

Picture of the nominees of Innovation award 2008 in front of the Liebermann Building/Pariser Platz in Berlin

Prof. Müller as representative of the nominated research consortium

Dr. C. Keck/PharmaSol GmbH, D. Karlowswki/P.M. Beyvers GmbH and Prof. Müller

Press release Freie Universität Berlin 13 November 2008:

Professor Rainer H. Müller für Innovationspreis Berlin-Brandenburg 2008 nominiert Pharmazeut der Freien Universität Berlin entwickelt ultrafeine Wirkstoffkristalle

Nr. 361/2008 vom 13.11.2008

Rainer H. Müller, Professor für Pharmazeutische Technologie am Institut für Pharmazie der Freien Universität Berlin, ist für den Innovationspreis Berlin-Brandenburg 2008 nominiert worden. Die gemeinsame Bewerbung des Wissenschaftlers mit den Unternehmen PharmaSol GmbH und P.M. Beyvers GmbH wurde unter 142 Bewerbungen ausgewählt. Die Auszeichnung wird im Dezember 2008 an maximal fünf Preisträger vergeben und ist mit jeweils 10.000 Euro dotiert.

Nominiert wurde Professor Rainer H. Müller für die Entwicklung sogenannter Nanodiamanten. Diese ultrafeinen Kristalle erhöhen die Löslichkeit und die biologische Aktivität schwer löslicher Natur- und Arzneistoffe. Dies gelingt, indem Partikel eines Wirkstoffes von Makrogröße in die Nanodimension verkleinert werden (ein Nanometer ist ein Milliardstel Meter). Durch diese Verkleinerung erhalten die Substanzen neue physikalische Eigenschaften, etwa eine größere Oberfläche und eine bessere Löslichkeit. Die Technologie, um diese Nanodiamanten zu erzeugen, entwickelte Professor Rainer H. Müller auf der Basis der Hochdruckhomogenisation, bekannt von homogenisierten Lebensmitteln. Für die Produktion von Nanokristallen ist dabei ein hoher Homogenisationsdruck von bis zu 1.500 bar erforderlich (zum Vergleich: ein Autoreifen hat etwa zwei bar). Erste Studien mit dem Kosmetikwirkstoff Rutin in einer Hautcreme ergaben, dass Rutin-Nanokristalle eine 500-fach höhere Bioaktivität besitzen als das herkömmliche wasserlösliche Rutinglycosid.

Der Innovationspreis wird von den Ländern Berlin und Brandenburg gemeinsam mit der Wirtschaft der Hauptstadtregion in Public-Private-Partnership vergeben. Die Auszeichnung soll herausragende Innovationen würdigen und zielt auf eine Vernetzung von Forschung, Entwicklung und Unternehmen. Über Nominierungen und Preisträger entscheidet eine unabhängige Jury unter Vorsitz von Professor Manfred Hennecke, Präsident der Bundesanstalt für Materialforschung und -prüfung.

Weitere Informationen:

Professor Dr. Rainer H. Müller, Freie Universität Berlin, Institut für Pharmazie, Pharmazeutische Technologie, Telefon: 030 / 838-50678 , Telefax: 030 / 838-50701 , E-Mail: mpharma@zedat.fu-berlin.de

11^th June 2008: Rainer Müller und Monika Schäfer-Korting gewannen den Transferpreis WissensWerte

Tagesspiegel

PZ 25/2008:

DAZ 25/2008:

1^st June 2008 : Prof. Speiser: Vater der Pharma-Nanotechnologie an FU ausgezeichnet

Am 30./31. Mai fand im Henry-Ford Bau der FU der European Workshop on Particulate Systems (EWPS) statt. EWPS ist das Nano-Meeting führender europäischer pharmazeutischer Institute in der Nanotechnologie, an der FU organisiert von Prof. R. H. Müller und Dr. C. M. Keck, FU-Pharmazie (www.muller-berlin.com). Bei der Eröffnungsfeier zum zehnjährigen Jubiläum von EWPS wurde der Schweizer Professor Dr. Peter P. Speiser mit dem „Lifetime Achievement Award for Pioneering Work on Nanosystems“ ausgezeichnet. Die Laudatio hielt Prof. Dr. R. Gurny vom Pharmazeutischen Institut in Genf.

Nanopartikel werden in der Pharmazie vielfältig eingesetzt, vom gezielten Transport der Arzneistoffe zum Wirkort („Nanotaxis“) bis hin zur Gentherapie. Prof. Speiser hat in der Promotionsarbeit seines Doktoranden Dr. Birrenbach an der ETH Zürich 1973 zum ersten Mal pharmazeutisch den Begriff „Nanokapsel“ (nanocapsule) benutzt, was als der Beginn der pharmazeutischen Nanotechnologie zur kontrollierten Wirkstoffapplikation gesehen werden kann. Viele weitere Arbeiten folgten bis zu seiner Pensionierung mit 72 Jahren. Der heute 88 jährige Prof. Speiser eröffnete offiziell EWPS mit einem brillianten Überblick zur Situation der pharmazeutischen Nanotechnologie.

Rund 60 Wissenschaftler aus 8 europäischen Ländern nahmen am Kongreß teil, über 40 wissenschaftliche Beiträge wurden präsentiert (www.ewps.org). Ausgewählte Vorträge werden in einem Sonderheft des International Journal of Pharmaceutics publiziert werden. Für seinen essentiellen Beitrag zur Etablierung von EWPS während der letzten zehn Jahre wurde Prof. Sandy Florence von London mit dem „Founders Award for important contributions to the development of EWPS“ ausgezeichnet. Das nächste EWPS Meeting findet im Mai 2010 in Paris statt. Da EWPS in Berlin gegründet wurde, findet die Zwanzigjahrfeier – schon jetzt von den Organisatoeren festgelegt – dann wieder an der FU Berlin statt.

Für Nachfragen steht zur Verfügung: Prof. Dr. Rainer H. Müller, Institut für Pharmazie, Kelchstr. 31, Tel. =30 – 838 506 78, Fax: 030 – 838 506 16, mail: nanoteam@gmx.com, homepages: www.muller-berlin.com, www.ewps.org

30 – 31 May 2008 : European Workshop on Particulate Systems (EWPS)

At the end of May Professor Müller and Dr. Keck organize EWPS in Berlin, this event will celebrate “one decade EWPS”. EWPS is the research network of leading institutes of pharmaceutical technology and biopharmaceutics in different countries of Europe. EWPS focuses on nanotechnology, that means nanocarriers which deliver drugs in an optimized way, ideally transport drugs to their desired site of action (drug targeting). The meeting will be opened by Professor Dr. P.P. Speiser from Switzerland, the father of polymeric pharmaceutical nanoparticles for drug delivery. Vice president Professor Dr. M. Schäfer-Korting will deliver a welcome address on behalf of the Free University of Berlin. The meeting is sponsored by the Free University of Berlin and the European Association of Pharma Biotechnology (EAPB) as academic sponsors and from pharmaceutical and cosmetic industry. The sponsoring companies are Juvena Switzerland, PharmaSol GmbH Berlin and Soliqs/Abbott Germany/US as platinum sponsors and Brookwood/Alabama in US and Dr. Rimpler GmbH/Wedemark in Germany as gold sponsors.

1st February 2007 : NLC technology/nanopearls in the press
The nanolipid carrier (NLC) technology developed by Prof. Rainer H. Müller has meanwhile been introduced to almost 20 cosmetic products on the cosmetic market. The first products were introduced by Dr. Rimpler GmbH/Germany. The cosmetic trade name of these lipid nanoparticles is Nanopearls. The cosmetic journal "Kosmetik International" published an interview and product information about NLC/Nanopearls in the issue January 2007.

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5th January 2007 : Cooperation Dr. Rimpler GmbH and Prof. Müller/FU
The concept of lipid nanoparticles was developed by Prof. Müller and his research group. The nanostructured lipid carriers (NLC) were developed as second generation in 1999/2000. In lipid nanoparticle technology the same concept was followed as with the liposomes. They appeared first in cosmetic products (Dior, 1986) before they entered the pharmaceutical market. In cooperation with Dr. Rimpler the first NLC-based cosmetic product was realised in 2004 (product Nanorepair, cosmetic line "Dr. Rimpler Kosmetik"). In the year 2006 the next products followed in the cosmetic line "Isabelle Lancray, Paris". In 2006 the product developed by Dr. Rimpler based on Prof. Müller's NLC technology was awarded with the so-called "Cosmetic Oscar" for the "most innovative cosmetic product of the year 2006". That means the year 2006 was very successful for Dr. Rimpler, this is especially nice because it is the 20 year anniversary of the Dr. Rimpler cosmetic line and the 60 year anniversary of the line "Isabelle Lancray" (summary article in BEAUTY FORUM 12/2006).

11th December 2006 : Prof. Müller's NLC technology: triple "Cosmetic Oscar" winner
Parallel zur Nominierung für den Innovationspreis Berlin-Brandenburg erhielt die Nanolipid-Technologie im dritten Jahr hintereinander den jährlichen Innovationspreis des BSB Verlags Dr. Riedel/Hamburg. Eine internationale Jury mit Vertretern wichtiger kosmetischer Firmen wählt in verschiedenen Kategorien den Innovationspreis. Die Nanolipid-Technologie erhielt 2004 den Preis für „den innovativsten kosmetischen Rohstoff“, im Jahr 2005 die Anerkennung für das „beste wissenschaftliche Fortbildungsseminar“ und kürzlich den Preis für „das innovativste kosmetische Produkt des Jahres 2006“. Aufgrund des Designs des Preises wird er in kosmetischen Fachkreisen als der „Kosmetik-Oscar“ bezeichnet. Die NLC-Technologie ist somit „3-facher Oscar-Gewinner“ in drei aufeinanderfolgenden Jahren.

11th December 2006 : Innovation prize nomination Berlin-Brandenburg
Nanostrukturierte Lipid-Carrier (NLC) sind winzige Nanopartikel mit einem Durchmesser kleiner als einhunderttausendstel Millimeter. Sie bestehen aus verträglichen pflanzlichen festen Lipiden, z. B. dem hautpflegenden Carnauba-Wax und Ölen reich an Omega-3 und Omega-6 ungesättigten Fettsäuren. Diese „Nanolipid-Partikel“ transportieren als „Nanotaxis“ kosmetische und pharmazeutische Wirkstoffe besser in die Haut. Nanolipid-Kosmetika haben daher eine verbesserte Wirksamkeit.
Die „NanoLipid-Partikel als Transport- und Schutzsystem für Wirkstoffe“ wurden von 146 Einreichungen unter die 7 Nominierten für den Innovationspreis Berlin-Brandenburg 2006 ausgewählt. Die Entwicklung war ein Gemeinschaftsprojekt der Firma Chemisches Laboratorium Dr. Kurt Richter GmbH (CLR) und Herrn Prof. Dr. R. H. Müller von der Freien Universität Berlin.
Die Nominierten finden Sie hier.

NLC technology entered the cosmetic market In the nineties the first generation of lipid nanoparticles, the SLN (solid lipid nanoparticles) was developed by the research group of Prof. Müller, the second generation followed at the turn of the millenium, the NLC (nanostructured lipid carriers). The NLC have advantages compared to the first generation, e. g. improved loading capacity for actives.

The first two cosmetic products based on the NLC technology were introduced to the market by the company Dr. Rimpler GmbH in Wedemark/Hannover in Germany. The products NanoRepair Q10 Creme and NanoRepair Q10 Serum were introduced to the market during the cosmetic fair "Beauty" in Munich on 29/30 October 2005. More details about the technology and the products can be found in an article in EuroCosmetics 11/12 2005, page 28ff. Information about the company can be obtained from www.rimpler.de.

PhD student Franziska Rank - no. 58 - graduated
On Wednesday, 7 December 2005, the 58th PhD student in Prof. Müller's research group graduated: Dr. Franziska Rank. She obtained her PhD in the area quality management (QM), the title of the thesis was:
"Integrated Management System (IMS) for Quality Assuarance in Pharmaceutical Production - Analysis and Model Development".

The research was a joint project between Schering AG in Berlin and the pharmacy department/Free University of Berlin. The many joint research PhD projects going on between the pharmacy department and companies demonstrate that not only basic research but also applied research is being performed in Berlin.

16th July 2005 : 3rd Leaving Ball of pharmacy
The 3rd leaving ball will again be again be organised in the five star hotel Steigenberger. Patrons are again Prof. Müller / Free University and Alexander Djamal / Deutsche Ärztefinanz. As before main financial sponsors are Deutsche Ärztefinanz, SChering AG, hexal/ratiopharm and PharmaSol GmbH. A ticket is EUR 55,-, and includes all-inclusive buffet and drinks from 19.00 - 23.00 o'clock and also a free tombola ticket. For purchase please click here.

12 - 17 June 2005 - PharmSciFair and EAPB :
The first pharmaceutical Sciencefair (PharmSciFair) takes place in Nice this year. It was initiated and mainly organised by the European Federation of Pharmaceutical Scientist (EFUPS). The concept of the PharmSciFair is that a number of different pharmaceutical congresses take place in parallel. Buy one ticket and get access to many conferences. Prof. Müller is general secretary of the European Association of Pharmabiotechnology (EAPB). EAPB will organize its 2nd PharmaBioTech Europe in Nice. Prof. Müller is one of the chairmen of PharmaBioTech, in addition the EAPB office in Berlin organizes an EAPB booth in Nice. EAPB has its official office in the department of Pharmaceutical Technology/Free University of Berlin.

1-3 June 2005 - Chair in Manchester / update :
By letter dated 30.March 2005 Prof. Müller received the offer of a chair in Biopharmaceutics and Biotechnology at the pharmaceutical department of the university of Manchester. Prof. Müller visited Manchester university for two days to discuss the offer by Manchester university in detail, i.e. the total of research money, equipment, labspace and new permanent staff for the research group. In addition, a new research concept was developed together with Prof. Gifford, head of school of pharmacy, and Prof. D. Gordon, vice president of Manchester University, which should give Manchester a unique position within the British pharmacy departments. Another equally important point was the curriculum of the pharmacy students. A concept was discussed with Prof. Gifford and Stirling, dean of education, to revise the curriculum, aim is to adept the content to the present needs of community pharmacy but also pharmaceutical companies. Especially education should be optimized considering industrial pharmaceutical needs to further increase the number of pharmacists in pharmaceutical industries and thus potentially compensating job losses in community in pharmacies due to structural changes in the health systems (reduction of standing for health systems).

14 April 2005 - Research cooperation Prof. Müller and CLR GmbH/Berlin :
A research cooperation was agreed between Prof. Müller and CLR Dr. Kurt Richter Laboratorien GmbH (CLR). The cooperation concerns development of cosmetic excipients based on nanostructured lipid carriers (NLC). One the two main research areas of Prof. Müller. One aim of the cooperation is to develop special large scale production lines to even process chemically sensitive cosmetic actives. Apart from financially supporting the research by Prof. Müller, CLR provides access to its industrial facilities to perform basic research.

5 April 2005 - Nano for life - Application, Consortium SLN :
The German Ministry of Research (BmBF) decided to promote nanotechnology in Germany with a special support programm, Nano for Life. With almost 30 million Euros research consortia are sponsored developing nanoparticle products in life sciences (pharmacy, medicine). The consortia should be industry driven, that means there should be academic partners, but the emphesis are a mixture of small/medium sized companies with larger companies. Innovative ideas should be developed to be placed as products on the market. Up to 50% of the costs of companies will be reimbursed in this programm,universities should receive 100% reimbursement of their costs. The research group of Prof. Müller is part of a consortium to develop products based on lipid nanoparticles. The consortium consists of four companies plus the research group of Porf. Müller.

3 April 2005 - Offer of chair in Manchester to Prof. Müller
The university of Manchester offered to Prof. Müller the chair in "Biopharmaceutics and Biotechnology" at the Pharmacy department. The university of Manchester was re-founded last year by uniting the two previous universities. Offical opening of the new university took place in the presence of her majesty the queen. Strategic target is to establish Manchester university as aleading university, the development are that the department of pharmacy should be one of the ten leading pharmacy institutes in the world. The faculty of medicine is currently appointing a number of professors to reach this development target. Part of the concept is also to provide the pharmacy with a new building The first research groups will move in within the next months, the building will be completed in june/july 2006 with total costs of about 16 million pound sterling (appr. 24 million Euro). Anticipated starting is 1st september 2005.

March 2005 : PCIE Paris ESB Oskar for Prof. Müller :
At the PCIE (Gabi fragen Konferenz Name) Prof. Müller obtained the "ESB-Oskar" for the "best international seminar in cosmetics". The topic of the seminar was "Solid lipid nanoparticles (SLN)for cosmetic use". The ESB-Oskar awards are yearly given by the company ESB Dr. Riedel Verlag /Hamburg. The jury is composed of representatives of major international cosmetic companies (e.g. Loreal, Chanel, Beiersdorff etc.). It was the second ESB Oskar fro Prof. Müller, after having received the "ESB-Oskar for the most innovative cosmetic excepient" in 2004.

March 2005 : PCIE Paris ESB Oskar for Dr. Sven Gohla
At the PCIE in Paris the "ESB-Oskar for the most innovative cosmetic exciepient" was awarded to Dr. Sven Gohla. Dr. Sven Gohla is head of formulation development at Juvena /Switzerland (Vice President of Research and Development), at the same time Dr. Gohla is "Habilitant" in the research group of Prof. Müller. The Oskar acknowloges the development of a new concept for anti-aging of the skin. (RS Müller)

5 February 2005 : 2nd "Leaving ball" of pharmacy students, 8th semester
The second leaving ball took place at the five star hotel Steigenberger in Berlin. The patrons were Prof. Müller from the Free University of Berlin and Alexander Djamal from the Deutsche Ärztefinanz. Members of the organisation team were mainly students from the 7th semester, two from the 8th semester. Sponsors were Deutsche Ärztefinanz, Schering AG, hexel/ratiopharm and PharmaSol GmbH/Berlin (in order of contribution). The ball attracted 200 guests. Among the guest were the Dean of the faculty Prof. Hilger, and the vice dean of the faculty Prof. Schäfer-Korting (faculty of Biology, Chemistry, Pharmacy), the president Dr. Bartezko of the Apothekerkammer and the chairman Mr. Wagner of the Apothekerverein Berlin. It was a great evening,the last guests left the ball at around 5 o'clock in the morning.

Biofuture-Preis - 1.5 Mio. Euro
Dr. Carsten Rudolph, cooperating scientist of Prof. Müller, reiceved the Biofuture Award 2005 by the German Ministry of Research and Development (BMBF). This prize is annually awarded to promote young scientists at the beginning of their career to develop to level research. The award involves 1.5 Mio. Euro per scientist. Since 1998 more than 50 scientists have been awarded with the Biofuture Award.
Dr. Rudoph studied pharmacy at Marburg University and obtained his PhD in Pharmaceutical Biotechnology under the supervision of Prof. R. H. Müller in Berlin. The PhD work was performed at the hospital at the University of Munich, co-supervised by Dr. J. Rosenecker. Dr. Rudolph continued his scientific work in Munich and in 2003 he started to build up his own research group. At the same time he is "Habilitand" in the research group of Prof. Müller at the Institute of Pharmaceutical Sciences, Free University of Berlin.

For more information please click here.

December 2004 - DFG network application brain targeting
In December 2004 an application was filled to the German Research council (DFG) to establish a DFG reseach network of DFG-Schwerpunktprogramm "Targeted drug delivery to the brain". This initiative was started by Prof. Müller in spring 2004. About 14 research groups from different disciplines all over Germany worked together to establish a concept having a sufficient quality to be acceptable as a topic by the DFG "Schwerpunktprogramm". At the end of the discussion process, about 30 research groups filed an application to improve delivery of drugs to the brain. The concept is based on the discovery by Prof. Kreuter / Frankfurt How to get nanoparticles across the blood brain barrier. Speaker of the group is Prof. Müller / Free University of Berlin, vice speaker is Prof. Fahr, pharmacy department at the university of Jena.

AAPS in Baltimore 7-11 November 2004
The American Association of Pharmaceutical Scientists (AAPS) has held its annual meeting in the convention centre in Baltimore/Maryland in USA. It was a successful annual meeting with about 8,000 participants. The research group of Prof Müller was represented by 12 poster presentations and one invited lecture given by Prof Müller personally.
The title of the presentation was Lipid nanoparticles for parenteral drug delivery.
The following members of the research team were presented the meeting: Torsten Göppert, Norma Hernández-Trejo, Conny Keck, Jan Möschwitzer and Eliana Souto.
The AAPS meeting is the most important conference for the research team of Prof Müller, especially with regard to establishing research contacts to pharmaceutical industry. The scientific AAPS meeting is accompanied by a company exhibition, about 1,000 companies are regularily present with a booth.

Baltimore: Meeting with Story Musgrave / NASA astronaut
Parallel to the AAPS annual conference in Baltimore, Prof Rainer H Müller and pharmacist Conny Keck met Dr Story Musgrave.
Dr Musgrave joined NASA as scientistastronaut in August 1967. Dr Musgrave is a veteran of six space flights, spending a total of 1,281 hours in space. His first flight was on space shuttle Challenger in 1983, followed by flights with the space shuttles Discovery and Endeavour. The Endeavour flight in 1993 was the first Hubble Space Telescope (HST) servicing and repair mission. During this 11-day flight, the HST was restored to its capabilities during a record of 5 space walks by the astronauts. Dr Musgrave performed 3 of these space walks.
Most recently, Dr Musgrave served aboard space shuttle Columbia. The most interesting topic addressed by Dr Musgrave in the discussion was the perfect separation of 2-dimensional electrophoretic gels, one of the major research areas of Prof Müller. In space it is possible to separate proteins in an ideal manor.

Annual meeting of Controlled Release Society (CRS) from 20-26 July 2004 in Honolulu/Hawaii.
The annual meeting of the Controlled Release Society (CRS) took place in Honolulu this year. CRS is the largest society in America to deal with general issues of controlled release in various areas, that means pharmacy but also for example cosmetics, food and agriculture.
The research group of Prof Müller presented a total of 4 poster contributions to this meeting. PhD students of Prof Müller attending this meeting were Conny Keck, Boris Petri and Felix Tröster.
Apart from scientific highlights, of course Honolulu had its striking features such as Waikiki Beach, a beautiful sand beach with nice palm trees and excellent cocktails in various bars located at the beach. Highly recommended, and attended, was the pub The Mouse having a happy hour from 4-8 p.m. All cocktails with the volume of 0.4 l (!) were served for prices ranging from 2.00 to 2.50 USD (equivalent to app 1.50€ to 2.00 €). The Mouse was heavily frequented not only by the research team from Berlin but also by other scientists.

July , 2004 - PhD student number 50 !
On Mr. Stefan Anger completed his PhD under the supervision of Prof. Müller. Mr. Anger was the PhD student number 50 concluding succesfully his thesis. The thesis was awarded with the best possible grade "summa cum laude". The picture shows Prof. Müller handing over the traditional "PhD present" of the research group, Galilea thermometer. The spheres of the thermometer are indicating the respective temperature, represent the nanoparticles, the major research topic of the group.

AAPS meeting in Salt Lake City 26-30 October 2003
The annual meeting of the American Association of Pharmaceutical Scientists (AAPS) in 2003 took place in Salt Lake City, Utah.
Utah is very well known more one state of the US. The research group of Prof Müller contributed a total of 16 poster presentations. The research team was represented by the PhD students Aslihan Akkar, Felix Tröster, Boris Petri, Anne Saupe, Ilona Buttle, Conny Keck, and Nadim Bushrab.
Salt Lake City is famous for the Mormon Temple and the Adjacent Mormon Conference Centre. The Mormon Conference Centre was especially built to gather many Mormons for one big convention once a year. Of course, access to nice bars and fun is limited, therefore in case you go to Salt Lake City you should buy a club card to have also pleasure in the clubs during the night. All members of the research team of Prof Müller were club members from the first day. To sum up: AAPS in Salt Lake City was a very successful meeting because new research ideas were created and research links established.

Pharmacy student protest, Dec. 1st - 5th 2003

Sept. 17th Boehringer Ingelheim - largest biotech plant Europe

Sept. 7th 2003 Prof. Müller meets Spielberg in London

2003 Berlin "Marathon" Relay 2003